Interrogating target-specificity by parallel screening of a DNA-encoded chemical library against closely related proteins.
نویسندگان
چکیده
Parallel affinity screening of a DNA-encoded chemical library against rat, bovine and human serum albumin allowed the identification of small-molecule ligands with distinctive binding specificities to the individual proteins.
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عنوان ژورنال:
- Chemical communications
دوره 51 38 شماره
صفحات -
تاریخ انتشار 2015